Ocu-Clear® Eye Vitamin AREDS 1 Formula by Thorne Research - Free Shipping    This product has been discontinued by the manufacturer.  Please see AREDS 2 Plus Zinc-Free by Eye Promise or Lutein and Greens by Carlson Labs for a replacement..   Ocu-Clear AREDS 1 Formula by Thorne Research is named after the National Eye Institute's Age Related Eye Disease Study (AREDS) and consists of the same general nutrients and quantities used in the study: Beta-carotene equivalent to 25,000 IU vitamin A Vitamin C 500 mg Vitamin E 400 IU Zinc 80 mg Copper 2 mg The combination of antioxidant vitamins, minerals, and carotenes provided in Ocu-Clear AREDS 1 Formula has been shown to support vision and promote eye health. Two Capsules Contain: Vitamin A (as Beta Carotene) 25,000 IU Vitamin C (as Ascorbic Acid) 500 mg Vitamin E (as d-Alpha Tocopheryl Acetate) 400 IU Zinc (as Zinc Citrate) 80 mg Copper (as Copper Citrate) 2 mg Other Ingredients: Hypromellose (derived from cellulose) capsule.  Suggested Use: Take 2 capsules daily or as recommended by your eye-care practitioner. Servings Per Container: 30 ALLERGY WARNINGS This product is contraindicated in an individual with a history of hypersensitivity to any of its ingredients. PURITY This product does not contain wheat, soy, gluten, corn, yeast, egg, dairy products, or artificial colors, sweeteners, or flavors. This product also does not contain lactose; palmitic acid; or magnesium, calcium or vegetable stearates. PREGNANCY If pregnant, consult your health-care practitioner before using this product. INTERACTIONS There are no known adverse interactions or contraindications at publication date.   These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.   Buy FRESH we are authorized distributors of the fine products we represent.  It pays to be well at Apple-A-Day-Clinic.com

multiple vitamin mineral preparations for women, men, cancer survivors, diabetes, heart health etc

Mediclear Plus by Thorne Research - Free Shipping   Holistic Doctor Recommended   Per the manufacturer, Thorne Research products are not available for sale online to the public.  Please call us for more information. Product Information Mediclear Plus by Thorne Research contains all the nutritional components of MediClear with the added advantages of curcumin phytosome, grape seed phytosome, and green tea phytosome – all well-absorbed forms of these plant extracts for maintenance of the body's normal inflammatory response. Our external environment has become increasingly more polluted in the last 50 years, causing a greater cumulative toxic burden in humans than ever before. Unavoidable exposure to thousands of toxic chemicals in the environment has delivered up the daunting task of detoxifying and eliminating these substances from our bodies. Added to this are the many internally produced substances (hormones, biochemical metabolites) the body must detoxify on a daily basis. The result is a serious challenge to our organs of elimination, particularly the liver. In addition to this ever-increasing toxic load, the over-consumption of fats and sugars – and our reliance on nutrient-depleted vegetables, grains, fruits, and antibiotic- and hormone-laden meats – adds to the toxic load while providing inadequate nutrients for many metabolic processes, especially detoxification. The liver carries the greatest share of the detoxification burden, as it is the liver's job to change potentially harmful substances into non-toxic, water-soluble compounds that can be eliminated by the kidneys or intestines. The liver and other tissues participating in the detoxification process must have available the proper nutrient cofactors to efficiently accomplish this task.* In addition, specific botanicals are useful in assisting detoxification by the liver.* What is Phase I/Phase II Liver Detoxification? In phase I of liver detoxification, fat-soluble substances are converted to intermediate metabolites mainly by a group of enzymes called cytochrome p450 enzymes. The intermediate molecules are often more reactive and potentially more toxic than the original substance. Phase II detoxification involves the attachment of other molecules onto these intermediate metabolites to make them non-toxic and water-soluble and allow their elimination via the urine or intestines. MediClear Plus by Thorne Research Provides Liver Support* Providing essential nutrient cofactors, while supplying an adequate amount of low-allergenicity protein, can be very beneficial to liver function.* Health-care practitioners know that many challenges to health can arise when a patient's liver is not functioning as it should, including poor digestion, imbalances in intestinal bacteria, and fatigue. MediClear Plus includes beneficial detoxification nutrient cofactors,* as well as an array of extra nutrients and botanicals in powder form that can be added to water, or fruit or vegetable juice, resulting in a pleasant-tasting beverage. Why Rice and Pea Protein? Rice and pea protein are used in MediClear Plus by Thorne Research because of their low incidence of allergenicity. It is far more likely for dairy or soy protein to initiate an allergic reaction. Using rice and pea proteins allows you to eliminate most allergenic proteins from the diet, yet maintain high-quality protein intake Detoxification Cofactors MediClear Plus by Thorne Research contains vitamins and minerals necessary for detoxification and liver support.* These nutrients are provided in the most absorbable, best utilized forms, such as calcium and magnesium citrate-malate, pyridoxal 5'-phosphate (active vitamin B6), folinic acid and L-5-MTHF (active forms of folate), methyl- and adenosylcobalamin (active forms of B12), and UltraChrome (Thorne's patented chromium).*   Ingredients Two Scoops (46 g) Contain: Calories 180 Calories from Fat 35 Total Fat 3.5 g. Saturated Fat 2 g. Cholesterol 0 mg. Total Carbohydrate 5 g. Sugars 1 g. Dietary Fiber 2 g. Protein 32 g. Vitamin A (3,000 IU from Mixed Carotenes and 2,000 IU as Palmitate) 5,000 IU. Vitamin C (as Ascorbic Acid) 300 mg. Vitamin D (as Vitamin D3) 400 IU. Vitamin E (70 IU from Mixed Tocopherols and 50 IU from d-alpha Tocopherol)120 IU. Thiamin (as Thiamin HCl) 12 mg. Riboflavin (as Riboflavin 5'-Phosphate Sodium) 5 mg. Niacin (30 mg as Niacinamide and 8 mg as Niacin) 38 mg. Vitamin B6 (as Pyridoxal 5'-Phosphate) 10 mg. Folate (150 mcg as Calcium Folinate and 150 mcg as L-5-Methyltetrahydrofolate from L-5-Methyltetrahydrofolic Acid, Glucosamine Salt)300 mcg. Vitamin B12 (25 mcg as Adenosylcobalamin and 25 mcg as Methylcobalamin)50 mcg. Biotin 150 mcg. Pantothenic Acid (as Calcium Pantothenate) 50 mg. Calcium (as Calcium Citrate-Malate) 300 mg. Phosphorus 314 mg. Magnesium (as Magnesium Citrate-Malate) 150 mg. Zinc (as Zinc Picolinate) 10 mg. Selenium (as Selenomethionine) 70 mcg. Manganese (as Manganese Picolinate) 1.5 mg. Chromium (as Chromium Chelidamate Arginate)* 100 mcg. Molybdenum (as Molybdenum Picolinate) 50 mcg. Potassium (as Potassium Citrate-Malate) 300 mg. Glycine** 1.65 g. Medium Chain Triglycerides (MCTs) 1.5 g. L-Glutamine** 500 mg. L-Lysine (as L-Lysine Monohydrochloride)** 500 mg. Curcumin Phytosome*** (Curcuma longa extract (root) / Phosphatidylcholine complex) 400 mg. Quercetin 250 mg. Taurine** 110 mg Methyl Sulfonyl Methane (MSM) 100 mg. Grape Seed Phytosome*** (Vitis vinifera extract / Phosphatidylcholine complex) 50 mg. Green Tea Phytosome*** (Camellia sinensis extract (leaf) / Phosphatidylcholine complex) 50 mg. Bacillus coagulans**** 50 mg. Betaine Anhydrous (Trimethylglycine) 50 mg. N-Acetyl-L-Cysteine** 50 mg. Choline Citrate 30 mg. Glutathione (Reduced)** 25 mg. Boron (as Boron Picolinate) 100 mcg. Vanadium (as Vanadium Picolinate) 50 mcg. Other Ingredients: Pea Protein, Rice Protein, Rice Bran, Silicon Dioxide. *Thorne's trade name for Chromium (4 oxopyridine,2,6-dicarboxylate, arginate) is UltraChrome®. Its use in this product is protected by U.S. Patent No. 5,665,385. **ADDED AMINO ACIDS ***This product uses Indena S.p.A.'s green tea phytosome (Greenselect®), grape seed phytosome (Leucoselect®), and curcumin phytosome (Meriva®). Greenselect, Leucoselect, and Meriva are registered trademarks of Indena S.p.A. ****Lactobacillus sporogenes (alternate nomenclature)  Contains ingredients derived from soy (phytosomes). Suggested Use: For adults and children 12 or more years of age. Mix 2 scoops with 8 ounces of cold water, vegetable or fruit juice, rice milk, or nut milk 1-3 times daily. This product is not a medical food. It is intended to be utilized in conjunction with a complete dietary program. Do not use in diets supplying less than 600 calories per day without complete medical supervision. Servings Per Container: 20 Statements and Warnings ALLERGY WARNING This product is contraindicated in an individual with a history of hypersensitivity to any of its ingredients. MediClear Plus by Thorne Research contains green tea phytosome, curcumin phytosome, and grape seed phytosome - plant extracts complexed with phosphatidylcholine, which is derived from soy. Phosphatidylcholine contains no soy protein. There are no other soy-based ingredients in MediClear Plus. EXCIPIENT FREE This product does not contain wheat, gluten, corn, yeast, egg, dairy products, or artificial colors, sweeteners, or flavors. This product also does not contain lactose, palmitic acid, or magnesium, calcium, or vegetable stearates. PREGNANCY WARNING If pregnant, consult your health-care practitioner before using this product. INTERACTIONS/CONTRAINDICATIONS Folinic acid and 5-methyl-tetrahydrofolate supplementation is not recommended concurrently with methotrexate cancer therapy, as they can interfere with methotrexate's anti-neoplastic activity; however, these folate sources have not been shown to interfere with the anti-inflammatory activity of methotrexate. An individual taking methotrexate for psoriasis or rheumatoid arthritis can safely take a supplement containing folate. Curcumin has been shown to reduce the therapeutic efficacy of cyclophosphamide (Cytoxan) in animal studies. In vitro research revealed that curcumin decreased camptothecin-induced death of cultured breast cancer cells. Curcumin might also interfere with the absorption and efficacy of the chemotherapy drug irinotecan, used to treat colon cancer. The concurrent use of curcumin with these agents should be avoided. OTHER WARNING This product is intended to be utilized in conjunction with a complete dietary program. Do not use in diets supplying less than 600 calories per day without complete medical supervision.   These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.   Buy FRESH authorized products.  We are an authorized distributor of Thorne Research and other fine brands.  Questions?  Ask the Naturopathic Doctor/Dietician Nutritionist!  

Basic Prenatal by Thorne Research - Free Shipping   Per the manufacturer, Thorne Research products are not available for sale online to the public.  Please call us for more information.   Holistic Doctor Recommended Product Information Pregnancy is a critical time for optimizing health and nutrition, both for the mother and her baby. Overall nutritional and caloric needs are greatly increased by pregnancy and breastfeeding.* However, especially during the first trimester because of nausea, women are not always able to consume the desired number of calories or variety of nutrients. Several nutrients in a good prenatal multiple vitamin have been found to benefit pregnant women who suffer from "morning sickness," including vitamin C, vitamin B6, and vitamin K.* The Centers for Disease Control and Prevention recommend folic acid supplementation for all women of childbearing age because the biggest need is during the first trimester, when a woman may not even be aware she is pregnant. A woman who consumes a healthful diet with adequate folate may reduce her risk of having a child with a birth defect of the brain or spinal cord. Folate intake should not exceed 250 percent of the government's recommended daily value (1,000 mcg). The need for other nutrients, such as iron, increases dramatically during pregnancy and is not always compensated for by diet alone.* Multiple vitamin supplementation – during the year before becoming pregnant, during pregnancy, and while breastfeeding – can help produce a healthy baby and benefit the mother through labor, delivery, breastfeeding, and postpartum.* Basic Prenatal by Thorne Research is a comprehensive supplement formulated with the special needs of pregnancy in mind. Manufactured with none of the additives and coatings usually found in mainstream prenatal tablets, Basic Prenatal includes only the most bioavailable nutrients. High-potency multiple vitamins may sometimes be difficult for a woman to "stomach," particularly during the first trimester of pregnancy. Therefore, Thorne does not include large amounts of the nutrients commonly known to cause stomach upset. Instead, these nutrients are included in their most active or absorbable forms for superior utilization.* Among these are the active forms of several of the B vitamins – pyridoxal 5'-phosphate (vitamin B6), riboflavin 5'-phosphate (vitamin B2), folinic acid and L-5-MTHF (active forms of folate), and adenosylcobalamin and methylcobalamin (vitamin B12). Calcium in large doses may also cause stomach upset. Therefore, a moderate dose in the highly absorbable citrate-malate form is used. Additional calcium and magnesium can be supplemented, especially in the final trimester. Basic Prenatal by Thorne Research may also be taken by nursing mothers.   Statements and Warnings ALLERGY WARNINGS Basic Prenatal by Thorne Research is contraindicated in an individual with a history of hypersensitivity to any of its ingredients. Iodine may occasionally cause an allergic reaction in some individuals. PURITY Basic Prenatal by Thorne Research does not contain wheat, gluten, corn, yeast, soy, egg, dairy products, or artificial colors, artificial sweeteners, or artificial flavors. This product also does not contain lactose, palmitic acid, magnesium stearate, or stearic acid. PREGNANCY If pregnant, consult your health-care practitioner before using Basic Prenatal by Thorne Research. INTERACTIONS As vitamin K interferes with the effect of anticoagulant drugs (like Coumadin), the concurrent use of these agents should be avoided. Folinic acid and 5-methyltetrahydrofolate supplementation is not recommended concurrent with methotrexate cancer therapy, as they can interfere with methotrexate's anti-neoplastic activity; however, these folate sources have not been shown to interfere with the anti-inflammatory activity of methotrexate. An individual taking methotrexate for psoriasis or rheumatoid arthritis can safely take a supplement containing folate. ADDITIONAL WARNINGS Accidental overdose of iron-containing products is a leading cause of fatal poisoning in children under six. Keep this product out of reach of children. In case of accidental overdose, call a doctor or poison control center immediately. Vitamin C can cause diarrhea in some individuals in large doses, which can vary from person to person and resolves when the amount is reduced.    Some customers have noted that this formula has a strong odor. This is particularly noticeable to patients who have been taking it long-term. The change in odor is due to the fact that we have (over the past year) changed from selenium picolinate to selenomethionine. While we believe selenomethionine is a superior form of selenium, it does have a bit of a sulfur smell, which is normal and does not reflect a problem with the product.   These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease. Buy FRESH authorized products. We are an authorized distributor of Thorne Research and other fine brands. Questions? Ask the Naturopathic Doctor/Dietician Nutritionist!  

D-5000, Vitamin D-5000 by Thorne Research - Free Shipping Per the manufacturer, Thorne Research products are not available for sale online to the public.  Please call us for more information.   Holistic Doctor Recommended  Product Information It is essential to maintain healthy vitamin D levels throughout all stages of life, from fetal development to old age.* D-5000 by Thorne Research helps protect a number of important functions in the body.* The current recommended daily vitamin D intake of 400 IUs is based on the minimum allowance to protect against bone disease. However, an upward revision of the FDA's guideline is now under consideration in light of new research, especially pertaining to immune function. Cutting-edge research suggests serum vitamin D levels should be in the range of 32-80 ng/mL 25-hydroxyvitamin D (25(OH)D). Although direct sunlight exposure is a good source of vitamin D, many people do not get enough sun due to season change, latitude, or lifestyle. Therefore, vitamin D supplementation can be of great benefit in these cases.* Vitamin D deficiency is quite common, particularly among the elderly.* For example, a study conducted at a hospital in Glasgow, Scotland, found an almost universal vitamin D deficiency among a group of 548 elderly patients. Individuals deficient in vitamin D may need 5,000-10,000 IU of vitamin D daily to replenish tissue stores.* With these individuals specifically in mind, Thorne's D-5,000 supplies 5,000 IU of pure vitamin D3 in each vegetarian capsule. Some vitamins, because of their potency, are usually given in very small amounts. Examples of such "micro-dose" vitamins include vitamin D, vitamin K, and vitamin B12. Most dietary supplement manufacturers purchase "micro-dose" vitamins from raw material suppliers as premixed dilutions, meaning the vitamins (in powder form) are mixed with other powdered substances that in turn make it easier for the manufacturer to handle and mix a larger quantity of raw material. Unfortunately, the powdered substances used in these premixed dilutions frequently contain potentially detrimental ingredients such as lactose and also the preservatives BHT, BHA, sodium benzoate, and sorbic acid. At Thorne Research, our promise is to give you the purest supplements humanly possible. Therefore, we do not purchase premixed dilutions of any "micro-dose" vitamins. Instead, we purchase pure, undiluted vitamins and create our own dilutions when it is necessary to do so, using pure, hypoallergenic powders, such as magnesium citrate or plant cellulose. The resultant premixture is then added to the dietary supplement being made, ensuring the proper amount of each pure nutrient is contained in each capsule.   Ingredients 60 Vegetarian Capsules One Capsule Contains: Vitamin D (as Vitamin D3) 5,000 IU Other Ingredients: Microcrystalline Cellulose, Hypromellose (derived from cellulose) capsule, Leucine, Silicon Dioxide, Vitamin E (mixed tocopherols).  Suggested Use: Take 1 capsule one to three times daily or as recommended by a health-care practitioner. Statements and Warnings ALLERGY WARNING D-5000 by Thorne Research is contraindicated in an individual with a history of hypersensitivity to any of its ingredients. PURITY D-5000 by Thorne Research does not contain wheat, gluten, corn, yeast, soy, egg, dairy products, or artificial colors, artificial sweeteners, or artificial flavors. This product also does not contain lactose, palmitic acid, magnesium stearate, or stearic acid. PREGNANCY WARNING If pregnant, consult your health-care practitioner before using D-5000 by Thorne Research. INTERACTIONS There are no known adverse interactions or contraindications at publication date.   These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease. Buy FRESH authorized products. We are an authorized distributor of Thorne Research and other fine brands. Questions? Ask the Naturopathic Doctor/Dietician Nutritionist!  

SpectraCell's Micronutrient Test Panel - Free Shipping Holistic Doctor Recommended Before the introduction of our tests, many diagnosis and risk assessments were based on clinical observation and measurements of static levels of certain nutrients in serum. Static serum levels are not always representative indicators for assessing cell metabolism and utilization.   SpectraCell’s micronutrient testing offers a unique means to scientifically assess the intracellular requirements of micronutrients that play an important role in overall health and wellness of your patients. Our tests measure the biochemical function of vitamins, minerals, amino acids and antioxidants, providing a powerful clinical assessment tool for your practice.   Our panels are designed to provide you with the most comprehensive nutritional analysis available. As the only lab that can offer a truly functional intracellular testing, SpectraCell also provides you with targeted nutrient repletion recommendations for those vitamins and minerals found to be deficient.   No consultation is included with this test, results will be sent to you. To have your results evaluated and receive diet and supplement recommendations, please contact us to schedule a consult with our Naturopath/Nutritionist!   Required Statement: Test kits and consultations are for educational purposes and are not intended to diagnose, treat, cure, or prevent any disease.   Test kits are not included in our bulk savings program.

Ionic Zinc by Trace Minerals Research - Free Shipping   Dietary Supplement   Holistic Doctor Recommended Ionic Zinc is a rich, concentrated liquid dietary supplement that provides 50mg of zinc sulfate per serving in an ionic form–the form most widely recognized by the body. The balanced liquid form provides safety and flexibility.† An adequate supply of zinc is essential for growth and physical development, especially as it relates to proteins, fats and carbohydrates.    Serving Size 1.25mL Servings per Container  48   Amount Per Serving Magnesium (from ConcenTrace)            25mg Zinc (as Zinc Sulfate)                           50mg Copper (as Copper Sulfate)                     2mg Chloride (from ConcenTrace)                 70mg Sulfate (from ConcenTrace, Zn Sulfate)  60mg Boron (from ConcenTrace)                   0.1 mg   Other ingredients: Purified water, ConcenTrace, citric acid, potassium benzoate, less than 0.1%   Suggested Use: Shake well. Using the metered dropper, take 0.5-1.25 mL daily with juice/food to mask the concentrated mineral flavor. Due to the concentrated nature of this product, we recommend spreading the serving size throughout the day and taking it on a full stomach. Refrigeration not necessary.     Allergen Info: contains no known allergens. GLUTEN FREE. CERTIFIED VEGAN.

An essential nutrient or nutrients that the body requires on a regular basis in order to repair itself and go about its daily functions.

Vitamin D/K2 by Thorne Research - Free Shipping Holistic Doctor Recommended. Per the manufacturer, Thorne Research products are not available for sale online to the public.  Please call us for more information. Product Information  Thornes, Vitamin K2 exerts a more powerful influence on bone than does vitamin K1.* Vitamin K2 is a series of molecules known as menaquinones. The most common and well studied of the menaquinones is MK-4. Thorne's vitamin K2 is MK-4. Vitamin K is also essential for normal cell formation and maintenance of a healthy cardiovascular system.* It is essential to maintain healthy vitamin D levels throughout all stages of life, from fetal development to old age.* Vitamin D helps protect a number of important systems in the body, including healthy bones, immunity, and cardiovascular function.* Combining vitamins D and K may provide even better protection of these systems.* One study in postmenopausal women found a combination of minerals with vitamins D and K maintained healthy artery elasticity, compared to two other groups of women who received either minerals with vitamin D but not K, or placebo.* Thorne's Vitamin D / K2 Liquid is in medium chain triglyceride oil, preserved with mixed tocopherols.   Ingredients Two Drops Contain: Vitamin D (as Vitamin D3) 1,000 IU. Vitamin K (as Vitamin K2 (Menatetrenone))* 200 mcg. *MK4 Other Ingredients: Medium Chain Triglyceride Oil, Mixed Tocopherols.  Suggested Use: Take 2 drops one to three times daily or as recommended by a health-care practitioner. Servings Per Container: 600 Statements and Warnings ALLERGY WARNING Vitamin D/K2 by Thorne research is contraindicated in an individual with a history of hypersensitivity to any of its ingredients. PURITY Vitamin D/K2 by Thorne research does not contain wheat, gluten, corn, yeast, soy, egg, dairy products, or artificial colors, artificial sweeteners, or artificial flavors. This product also does not contain lactose, palmitic acid, magnesium stearate, or stearic acid. PREGNANCY WARNING If pregnant, consult your health-care practitioner before using this product. INTERACTIONS As vitamin K interferes with the effect of anticoagulant drugs (like Coumadin), the concurrent use of these agents should be avoided.   These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.   Buy FRESH authorized products.  We are an authorized distributor of Thorne Research and other fine brands.  Questions?  Ask the Naturopathic Doctor/Dietician Nutritionist!  

Arginine Plus Suppository by Zetpil - Free Shipping   Holistic Doctor Recommended Oral arginine stimulates the release of arginase. Arginase decreases the systemic availability of Nitric Oxide (NO) leading to poor vascular health, diabetes complications, and erectile dysfunction.* Research indicates that NO bioavailability is compromised in the aging human heart and vasculature.*     Potential of Zetpil Arginine Plus   Arginine is a precursor to Nitric oxide (NO) and its production/bioavailability decreases with age. Nitric Oxide is a powerful protector against vascular “traumas” such as inflammation, plaque build-up and blood clots (thrombosis) which lead to cardiovascular diseases. * Endothelial dysfunction has been implicated in age-associated issues such as memory loss, hypertension, stroke, erectile dysfunction, and renal dysfunction.* Arginine increases blood flow which improves wound healing.* * THESE STATEMENTS HAVE NOT BEEN EVALUATED BY THE FOOD AND DRUG ADMINISTRATION. THIS PRODUCT IS NOT INTENDED TO DIAGNOSE, TREAT, CURE, OR PREVENT ANY DISEASE.   Supplement Facts Each Zetpil™ Arginine Plus contains the following ingredients:   L–Arginine (a proprietary blend of three of the most active forms of this free amino acid)           444mgs   Magnesium          160mgs   B3/Niacinamide    5mgs   B2/Riboflavin        5mgs   Folinic Acid           1.3mgs   **Note: Each Zetpil™ Arginine suppository is the equivalent of 4,000-5,000 mgs of oral Arginine.     Serving Size: 1 Suppository Servings Per Container: 60 Dosage and Use: 2 per day. This product can be taken at any time during the day, before retiring, or as directed by a healthcare professional. Suppository Base: The base is a proprietary combination of plant and fruit butters, vegetable acids, medium chain triglycerides, phospholipids, lecithin, vegetable starches, cellulose, oligosaccharides derivatives, polysaccharides and cycloamylose derivatives. This product contains an extract from soybeans making it contraindicated in individuals with a known hypersensitivity to phospholipids, sesame seed oils or any of the listed ingredients.   All suppositories are non refundable and non returnable.  No exceptions.   If you choose to use this product as a rectal suppository, it is highly recommended you attempt to clear your bowels prior to inserting it to avoid premature evacuation. To facilitate insertion it is recommended you moisten the product by passing it under a stream of cool water or use a personal lubricant. When used as a suppository, this product requires 15-20 minutes retention to ensure the complete absorption of the bioactive ingredients. This suppository can be inserted in any position. Although not required, if inserted while lying on one’s side, consider remaining in the supine position for 1-3 minutes following insertion. (Always insert flat end of suppository first).   WARNING   Although safe for children, this product should be kept out of the reach of children. Do not use if the suppositories are open or damaged. As with any nutrient if you are pregnant or breastfeeding, seek the advice of a health care provider before using this product. Individuals that have chosen to take this product as part of a personal nutrient program have overwhelmingly chosen to utilize this product as a rectal suppository or as a vaginal pessary. However, this product can also be taken safely by mouth. If one chooses to take this product orally, then this product may be considered a dietary supplement in accordance with current FDA guidelines.   Disclaimer: These statements have not been evaluated by the FDA. This product is a Federal Food, Drug, and Cosmetic Act compliant combination of naturally derived FDA GRAS (Generally regarded As Safe) herbal, nutraceutical, vitamins, minerals and amino acids products legally sold in the USA. In accordance with FDA regulations, when taken orally, this product may be considered a dietary supplement as defined by section 201(ff) of the Act, 21 U.S.C. § 321(ff).   Also, this product consists ONLY of a combination of naturally derived FDA GRAS (Generally regarded As Safe) herbal, nutraceutical, vitamins, minerals and amino acids products legally sold in the USA. Therefore, this product cannot be considered a drug as defined in section 201(g)(1) of the Act, 21 U.S.C. § 321(g)(1). This product is not intended to affect the structure or function of the body and is not intended for use in the diagnosis, cure, mitigation, treatment or prevention of disease in man. Any nutritional suggestions and research regarding this product are provided for informational purposes only, and are not intended to diagnose, treat, cure or prevent disease nor should any information provided be used as a substitute for sound medical advice.   The benefits of Arginine when delivered via suppository may include: Wound Healing:   Arginine has a positive influence on the body’s levels of insulin-like growth factor-I (IGF-I), a hormone that promotes wound healing. Arginine is a precursor to polyamines-the cell’s building blocks, which are important for wound repair. Arginine is the only substrate for nitric oxide synthesis. Nitric oxide has a beneficial effect on circulatory status and increases blood supply to the wound. Arginine contains immune-enhancing properties that reduce the risk of infectious complications of a wound. “Nitric oxide (NO) is critical in defending against infection and is a potent antimicrobial. Work in humans shows that topically delivered NO (Arginine is substrate for NO and bypasses arginase when delivered through the skin vs. oral delivery) is clinically useful and no more toxic than currently available antimicrobials.” http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3442839/   Blood Flow:   Arginine is crucial in the formation of endothelial Nitric Oxide Synthase (eNOS) that is required to maintain the plasticity of the endothelium (inner lining of blood vessels), repair the endothelium, and prevent the formation of fatty and atherosclerotic plaques. Nitric oxide is the endothelium-derived relaxing factor, causing the smooth muscle in the vessel wall to relax and the blood vessels to dilate. Adequate nitric oxide also helps to insure proper blood flow without increases in blood pressure. Nitric oxide increases blood flow to muscles to increase strength, endurance and overall muscle health. Arginine is an amino acid that is a growth hormone releaser. The decrease of growth hormone in the human body with aging is a major reason why muscle mass tends to decrease with age and body fat tends to increase with age. Neural Health:   Nitric oxide now also appears to be the neurotransmitter responsible for converting short-term memories to long-term memories in the brain. This is another ability that often declines with aging.