Refers to natural substances that remove waste or toxins from the human body.  These substances can be specific to: Liver detox, Colon detox, skin cleanse, heavy metal detox, IE cleanse or: Heavy metal detox.

Natural medicines derived from plants, which have been used to treat health conditions since the beginning of time. Some of our natural herbals are standardized meaning that have a predictable level of bio-activity.   Herbal medicines are used in naturopathic medicine, chinese medicine, homeopathy, flower essences, and ayurvedic medicine.

Mediclear Plus by Thorne Research - Free Shipping   Holistic Doctor Recommended   Per the manufacturer, Thorne Research products are not available for sale online to the public.  Please call us for more information. Product Information Mediclear Plus by Thorne Research contains all the nutritional components of MediClear with the added advantages of curcumin phytosome, grape seed phytosome, and green tea phytosome – all well-absorbed forms of these plant extracts for maintenance of the body's normal inflammatory response. Our external environment has become increasingly more polluted in the last 50 years, causing a greater cumulative toxic burden in humans than ever before. Unavoidable exposure to thousands of toxic chemicals in the environment has delivered up the daunting task of detoxifying and eliminating these substances from our bodies. Added to this are the many internally produced substances (hormones, biochemical metabolites) the body must detoxify on a daily basis. The result is a serious challenge to our organs of elimination, particularly the liver. In addition to this ever-increasing toxic load, the over-consumption of fats and sugars – and our reliance on nutrient-depleted vegetables, grains, fruits, and antibiotic- and hormone-laden meats – adds to the toxic load while providing inadequate nutrients for many metabolic processes, especially detoxification. The liver carries the greatest share of the detoxification burden, as it is the liver's job to change potentially harmful substances into non-toxic, water-soluble compounds that can be eliminated by the kidneys or intestines. The liver and other tissues participating in the detoxification process must have available the proper nutrient cofactors to efficiently accomplish this task.* In addition, specific botanicals are useful in assisting detoxification by the liver.* What is Phase I/Phase II Liver Detoxification? In phase I of liver detoxification, fat-soluble substances are converted to intermediate metabolites mainly by a group of enzymes called cytochrome p450 enzymes. The intermediate molecules are often more reactive and potentially more toxic than the original substance. Phase II detoxification involves the attachment of other molecules onto these intermediate metabolites to make them non-toxic and water-soluble and allow their elimination via the urine or intestines. MediClear Plus by Thorne Research Provides Liver Support* Providing essential nutrient cofactors, while supplying an adequate amount of low-allergenicity protein, can be very beneficial to liver function.* Health-care practitioners know that many challenges to health can arise when a patient's liver is not functioning as it should, including poor digestion, imbalances in intestinal bacteria, and fatigue. MediClear Plus includes beneficial detoxification nutrient cofactors,* as well as an array of extra nutrients and botanicals in powder form that can be added to water, or fruit or vegetable juice, resulting in a pleasant-tasting beverage. Why Rice and Pea Protein? Rice and pea protein are used in MediClear Plus by Thorne Research because of their low incidence of allergenicity. It is far more likely for dairy or soy protein to initiate an allergic reaction. Using rice and pea proteins allows you to eliminate most allergenic proteins from the diet, yet maintain high-quality protein intake Detoxification Cofactors MediClear Plus by Thorne Research contains vitamins and minerals necessary for detoxification and liver support.* These nutrients are provided in the most absorbable, best utilized forms, such as calcium and magnesium citrate-malate, pyridoxal 5'-phosphate (active vitamin B6), folinic acid and L-5-MTHF (active forms of folate), methyl- and adenosylcobalamin (active forms of B12), and UltraChrome (Thorne's patented chromium).*   Ingredients Two Scoops (46 g) Contain: Calories 180 Calories from Fat 35 Total Fat 3.5 g. Saturated Fat 2 g. Cholesterol 0 mg. Total Carbohydrate 5 g. Sugars 1 g. Dietary Fiber 2 g. Protein 32 g. Vitamin A (3,000 IU from Mixed Carotenes and 2,000 IU as Palmitate) 5,000 IU. Vitamin C (as Ascorbic Acid) 300 mg. Vitamin D (as Vitamin D3) 400 IU. Vitamin E (70 IU from Mixed Tocopherols and 50 IU from d-alpha Tocopherol)120 IU. Thiamin (as Thiamin HCl) 12 mg. Riboflavin (as Riboflavin 5'-Phosphate Sodium) 5 mg. Niacin (30 mg as Niacinamide and 8 mg as Niacin) 38 mg. Vitamin B6 (as Pyridoxal 5'-Phosphate) 10 mg. Folate (150 mcg as Calcium Folinate and 150 mcg as L-5-Methyltetrahydrofolate from L-5-Methyltetrahydrofolic Acid, Glucosamine Salt)300 mcg. Vitamin B12 (25 mcg as Adenosylcobalamin and 25 mcg as Methylcobalamin)50 mcg. Biotin 150 mcg. Pantothenic Acid (as Calcium Pantothenate) 50 mg. Calcium (as Calcium Citrate-Malate) 300 mg. Phosphorus 314 mg. Magnesium (as Magnesium Citrate-Malate) 150 mg. Zinc (as Zinc Picolinate) 10 mg. Selenium (as Selenomethionine) 70 mcg. Manganese (as Manganese Picolinate) 1.5 mg. Chromium (as Chromium Chelidamate Arginate)* 100 mcg. Molybdenum (as Molybdenum Picolinate) 50 mcg. Potassium (as Potassium Citrate-Malate) 300 mg. Glycine** 1.65 g. Medium Chain Triglycerides (MCTs) 1.5 g. L-Glutamine** 500 mg. L-Lysine (as L-Lysine Monohydrochloride)** 500 mg. Curcumin Phytosome*** (Curcuma longa extract (root) / Phosphatidylcholine complex) 400 mg. Quercetin 250 mg. Taurine** 110 mg Methyl Sulfonyl Methane (MSM) 100 mg. Grape Seed Phytosome*** (Vitis vinifera extract / Phosphatidylcholine complex) 50 mg. Green Tea Phytosome*** (Camellia sinensis extract (leaf) / Phosphatidylcholine complex) 50 mg. Bacillus coagulans**** 50 mg. Betaine Anhydrous (Trimethylglycine) 50 mg. N-Acetyl-L-Cysteine** 50 mg. Choline Citrate 30 mg. Glutathione (Reduced)** 25 mg. Boron (as Boron Picolinate) 100 mcg. Vanadium (as Vanadium Picolinate) 50 mcg. Other Ingredients: Pea Protein, Rice Protein, Rice Bran, Silicon Dioxide. *Thorne's trade name for Chromium (4 oxopyridine,2,6-dicarboxylate, arginate) is UltraChrome®. Its use in this product is protected by U.S. Patent No. 5,665,385. **ADDED AMINO ACIDS ***This product uses Indena S.p.A.'s green tea phytosome (Greenselect®), grape seed phytosome (Leucoselect®), and curcumin phytosome (Meriva®). Greenselect, Leucoselect, and Meriva are registered trademarks of Indena S.p.A. ****Lactobacillus sporogenes (alternate nomenclature)  Contains ingredients derived from soy (phytosomes). Suggested Use: For adults and children 12 or more years of age. Mix 2 scoops with 8 ounces of cold water, vegetable or fruit juice, rice milk, or nut milk 1-3 times daily. This product is not a medical food. It is intended to be utilized in conjunction with a complete dietary program. Do not use in diets supplying less than 600 calories per day without complete medical supervision. Servings Per Container: 20 Statements and Warnings ALLERGY WARNING This product is contraindicated in an individual with a history of hypersensitivity to any of its ingredients. MediClear Plus by Thorne Research contains green tea phytosome, curcumin phytosome, and grape seed phytosome - plant extracts complexed with phosphatidylcholine, which is derived from soy. Phosphatidylcholine contains no soy protein. There are no other soy-based ingredients in MediClear Plus. EXCIPIENT FREE This product does not contain wheat, gluten, corn, yeast, egg, dairy products, or artificial colors, sweeteners, or flavors. This product also does not contain lactose, palmitic acid, or magnesium, calcium, or vegetable stearates. PREGNANCY WARNING If pregnant, consult your health-care practitioner before using this product. INTERACTIONS/CONTRAINDICATIONS Folinic acid and 5-methyl-tetrahydrofolate supplementation is not recommended concurrently with methotrexate cancer therapy, as they can interfere with methotrexate's anti-neoplastic activity; however, these folate sources have not been shown to interfere with the anti-inflammatory activity of methotrexate. An individual taking methotrexate for psoriasis or rheumatoid arthritis can safely take a supplement containing folate. Curcumin has been shown to reduce the therapeutic efficacy of cyclophosphamide (Cytoxan) in animal studies. In vitro research revealed that curcumin decreased camptothecin-induced death of cultured breast cancer cells. Curcumin might also interfere with the absorption and efficacy of the chemotherapy drug irinotecan, used to treat colon cancer. The concurrent use of curcumin with these agents should be avoided. OTHER WARNING This product is intended to be utilized in conjunction with a complete dietary program. Do not use in diets supplying less than 600 calories per day without complete medical supervision.   These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.   Buy FRESH authorized products.  We are an authorized distributor of Thorne Research and other fine brands.  Questions?  Ask the Naturopathic Doctor/Dietician Nutritionist!  

Meriva-SR by Thorne Research - Free Shipping   Per the manufacturer, Thorne Research products are not available for sale online to the public.  Please call us for more information.   Holistic Doctor Recommended   Meriva-SR by Thorne Research is a unique, patented, time-release curcumin product. People throughout Asia have benefited from the healthful effects of curcumin for centuries. Curcumin is the orange pigment in turmeric (the primary ingredient in curry), and is a potent antioxidant that offers numerous health benefits, including supporting joint health and cardiovascular function, and helping to maintain the body's normal inflammatory response.* Whether taken as a supplement or from food, curcumin is generally poorly absorbed into the bloodstream. In conjunction with Indena S.p.A., the worldwide experts in botanical extract technology, we have uncovered the key to curcumin absorption – phytosome technology. Meriva curcumin phytosome is a unique curcumin extract that is significantly better absorbed than other curcumin extracts.* Phytosomes are plant extracts bound to phosphatidylcholine (PC), an essential component of human cells. Our bodies can make PC, but we can also get it from food or supplements. When taken orally, PC is very well absorbed. The scientists at Indena found a way to attach a curcumin extract to PC for superior absorption, resulting in Meriva. When you take Meriva your body absorbs the PC and the attached curcumin, resulting in more curcumin reaching the cells that can benefit from it.* A 2007 study published in the journal, Cancer Chemotherapy and Pharmacology, demonstrated Meriva's superior bioavailability compared to ordinary curcumin. Liver levels of curcumin were also higher with Meriva supplementation. A human study demonstrated 29-times greater bioavailability. In both studies, Meriva supplementation resulted in higher plasma concentrations of curcumin from a much smaller dose than with ordinary curcumin. In a recent eight-month human trial, Meriva was shown to support a healthy inflammatory response.* Individuals experienced improvements in clinical and biochemical end-points associated with joint health.* Several studies have illustrated curcumin's hepatoprotective effects, leading researchers to suggest its use in protecting the liver from exogenous insults from environmental toxins.* Curcumin also has the capacity to increase both the flow and solubility of bile.* Curcumin's hepatoprotective effects are due in part to direct free-radical scavenging; but curcumin also enhances the body's natural antioxidant system, which increases glutathione levels, thereby aiding in hepatic detoxification and inhibiting nitrosamine formation.*   Ingredients Two Capsules Contain: Curcumin Phytosome* (Curcuma longa extract (root) / Phosphatidylcholine complex) 500 mg Other Ingredients: High and low viscosity hydroxypropyl methylcellulose and CalciumCitrateLaurate, Hypromellose (derived from cellulose) capsule, Leucine, Silicon Dioxide, Microcrystalline Cellulose. *Curcumin Phytosome (Meriva®) complexed with Time-Sorb®, a time-release matrix. This product uses Indena S.p.A.'s curcumin phytosome (Meriva®). Meriva is a registered trademark of Indena S.p.A.  Contains ingredient derived from soy (phytosome). Suggested Use: Take 1-2 capsules two times daily or as recommended by a health-care practitioner. Servings Per Container: 60 Statements and Warnings ALLERGY WARNINGS This product is contraindicated in an individual with a history of hypersensitivity to any of its ingredients. Meriva-SR contains curcumin phytosome, a plant extract complexed with phosphatidylcholine, which is derived from soy. Phosphatidylcholine contains no soy protein. There are no other soy-based ingredients in Meriva-SR. PURITY This product does not contain wheat, gluten, corn, yeast, egg, dairy products, or artificial colors, artificial sweeteners, or artificial flavors. This product also does not contain lactose, palmitic acid, magnesium stearate, or stearic acid. PREGNANCY WARNING If pregnant, consult your health-care practitioner before using this product. INTERACTIONS Curcumin has been shown to reduce the therapeutic efficacy of cyclophosphamide (Cytoxan) in animal studies. In vitro research revealed that curcumin decreased camptothecin-induced death of cultured breast cancer cells. Curcumin might also interfere with the absorption and efficacy of the chemotherapy drug irinotecan, used to treat colon cancer. The concurrent use of curcumin with these agents should be avoided.   These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.   Buy FRESH authorized products.  We are an authorized distributor of Thorne Research and other fine brands.  Questions?  Ask the Naturopathic Doctor/Dietician Nutritionist!  

Thorne Research Professional Vitamins and Formulas.  

Choleast-900 by Thorne Research - Free Shipping   Per the manufacturer, Thorne Research products are not available for sale online to the public.  Please call us for more information.   Holistic Doctor Recommended Choleast-900 by Thorne Research contains Monascus purpureus, a red-pigmented yeast grown on rice. Numerous studies in China and the United States have demonstrated that red yeast rice preparations are helpful in maintaining healthy blood cholesterol levels.* This is important, as maintaining optimal cholesterol levels has been shown to be one component of maintaining good cardiovascular health.* Choleast-900 by Thorne Research contains consistent amounts of the naturally-occurring monacolins found in red yeast rice, without standardization or fortification. In addition to natural monacolins, red yeast rice contains the phytosterols beta-sitosterol, campesterol, and stigmasterol, as well as isoflavones and trace minerals, all of which can contribute to cardiovascular health.*   Ingredients Two Capsules Contain: Red Yeast Rice (Monascus purpureus) 1.8 g. Other Ingredients: Hypromellose (derived from cellulose) capsule, Leucine.  Choleast-900 by Thorne Research Contains ingredient derived from soy (rice). Suggested Use: Take 1-2 capsules two times daily or as recommended by a health-care practitioner. Servings Per Container: 60 Statements and Warnings ALLERGY WARNINGS Choleast-900 by Thorne Research is contraindicated in an individual with a history of hypersensitivity to any of its ingredients. Choleast-900 by Thorne Research contains an ingredient derived from soy. PURITY Choleast-900 by Thorne Research does not contain wheat, gluten, corn, egg, dairy products, or artificial colors, artificial sweeteners, or artificial flavors. This product also does not contain lactose, palmitic acid, magnesium stearate, or stearic acid. PREGNANCY WARNING If pregnant, nursing, or trying to conceive, do not use Choleast-900 by Thorne Research. INTERACTIONS There are no known adverse interactions or contraindications at publication date. ADDITIONAL WARNINGS Red yeast rice can cause gastritis, abdominal discomfort, and elevated liver enzymes. It is possible that reactions similar to those caused by HMG-CoA reductase inhibitor drugs (statins) can be caused by red yeast; however, those adverse reactions have not been reported for red yeast rice extracts. Choleast-900 by Thorne Research may cause a temporary and harmless red coloring of the stool.   These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease. Buy FRESH authorized products. We are an authorized distributor of Thorne Research and other fine brands. Questions? Ask the Naturopathic Doctor/Dietician Nutritionist!  

Lien Chiao Pai Tu Pian, Lien Qiao Pai Tu Pien, Lien Chiao Paitu, Forsythia Honeysuckle Detox - Free Shipping   Acupuncturist Recommended Lien Chaio Pai Tu Pien is a Chinese Herb, Chinese herbal Medicine also known as Forsythia/Honeysuckle. FOR: Skin Inflammation, itching allergy, eczema, dermatitis, psoriasis.  Removes itching by detoxing the skin.  See also Armadillo counter poison extract, Margarite Acne pill.   Lienchiaopaitu Pien supports the health of the skin, the gastrointestinal, circulatory, and immune systems, and the sensory nerves.   These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.   It pays to be well at Apple-A-Day-Clinic.com!  Free shipping on all orders!  Plus 10% off orders over $99, 15% off orders $151-199, and 20% off on all orders over $200! Discounts applied automatically upon check out.

FloraMend Prime Probiotic by Thorne Research - Free Shipping   Per the manufacturer, Thorne Research products are not available for sale online to the public.  Please call us for more information.   FloraMend Prime Probiotic by Thorne Research is a Holistic Digestive Doctor Recommended blend of natural, stable, human-strain probiotics to help replenish intestinal flora and promote overall digestive and immune health   30 Vegetarian Capsules OneFlora Mend Capsule Contains: Proprietary Blend 5 Billion Live Cells* Lactobacillus gasseri KS-13 Bifidobacterium longum G9-1 Bifidobacterium bifidum MM-2 Other Ingredients: Hypromellose (derived from cellulose) capsule, Potato Starch, Silica. *At time of expiration. Does not require refrigeration. Suggested Use: Take 1 capsule daily with a meal or as recommended by your health-care practitioner. FloraMend Prime Probiotic by Thorne Research is a dairy- and allergen-free proprietary blend of three essential strains of vital probiotics: Lactobacillus gasseri, Bifidobacterium bifidum, and Bifidobacterium longum. These strains are stabilized in a convenient, one-per-day dosage. Because of the unique culturing methods and proprietary combination of these strains, FloraMend Prime Probiotic by Thorne Research is stable at room temperature and does not need refrigeration. Floramend is provided in an acid-resistant capsule for effective delivery to the gut. To be effective, a probiotic supplement must (1) be viable at room temperature, (2) be able to withstand stomach acid, (3) be distributed throughout the intestinal tract, and (4) have the ability to adhere to the intestinal tract and reproduce.  FloraMend Prime Probiotic by Thorne Research shares these necessary characteristics and, taken daily, helps balance a healthy intestinal flora to promote a healthy intestinal environment for normal digestion and immune response.   ALLERGY WARNINGS FloraMend Prime Probiotic by Thorne Research is contraindicated in an individual with a history of hypersensitivity to any of its ingredients.   PURITY FloraMend Prime Probiotic by Thorne Research does not contain wheat, gluten, corn, yeast, soy, egg, dairy products, or artificial colors, artificial sweeteners, or artificial flavors. FloraMend Prime Probiotic by Thorne Research also does not contain lactose, palmitic acid, magnesium stearate, or stearic acid.   PREGNANCY WARNING If pregnant, consult your health-care practitioner before using FloraMend Prime Probiotic by Thorne Research.   INTERACTIONS There are no known adverse interactions or contraindications at publication date.   These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.   Buy FRESH authorized products.  We are an authorized distributor of Thorne Research and other fine brands.  Questions?  Ask the Naturopathic Doctor/Dietician Nutritionist!  

Immugen by Thorne Research - Free Shipping   Per the manufacturer, Thorne Research products are not available for sale online to the public.  Please call us for more information.   Holistic Doctor Recommended   Immugen by Thorne Research 120 caps   Immugen by Thorne Research is a Pet Supplement   Immugen by Thorne Research for Animal Health Immugen by Thorne Research for Immune Support   Directions for use: Cats: 1/2 capsule daily Dogs: 1 capsule per 25 lbs body weight daily   PRODUCT FACTS Active Ingredients per Capsule: Ascorbic Acid (Vitamin C) 175 mg Dimethylglycine (Hydrochloride) 70 mg L-Glutamine 70 mg N-Acetyl-L-Cysteine 70 mg Echinacea angustifolia (root) 50 mg Reishi Mushroom (Ganoderma lucidum) 50 mg d-Alpha Tocopheryl (Vitamin E) (35 IU) 30 mg Astragalus extract (root) (Astragalus membranaceus) 3.5 mg Thymus (Bovine) 25 mg Coenzyme Q10 20 mg Pyridoxal 5’-Phosphate (Vitamin B6) 7 mg Vitamin A Palmitate (1,400 IU) 5.6 mg Zinc (Picolinate) 3.5 mg Mixed Carotenes (Vitamin A) (1,400 IU) 840 mcg Copper (Picolinate) 350 mcg Folic Acid 200 mcg Manganese (Picolinate) 175 mcg Cyanocobalamin (Vitamin B12) 100 mcg Selenium (Selenomethionine) 7 mcg Inactive ingredients: Hypromellose (derived from cellulose) capsule, Leucine, Alaska pollock (dried skins) (Theragra chalcogramma), Silicon Dioxide.   Cautions: Safe use in pregnant animals or animals intended for breeding has not been proven. If animal’s condition worsens or does not improve, stop product administration and consult your veterinarian. Federal law prohibits the off-label use of this product in ruminants. Potential drug interactions. Potential interactions with CYP1A2 & CYP3A drugs. Not recommended for long-term use.   Warnings: For animal use only. Keep Immugen by Thorne Research out of the reach of children and animals. In case of accidental overdose, contact a health professional immediately.   These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease. Buy FRESH authorized products. We are an authorized distributor of Thorne Research and other fine brands. Questions? Ask the Naturopathic Doctor/Dietician Nutritionist!  

Basic Prenatal by Thorne Research - Free Shipping   Per the manufacturer, Thorne Research products are not available for sale online to the public.  Please call us for more information.   Holistic Doctor Recommended Product Information Pregnancy is a critical time for optimizing health and nutrition, both for the mother and her baby. Overall nutritional and caloric needs are greatly increased by pregnancy and breastfeeding.* However, especially during the first trimester because of nausea, women are not always able to consume the desired number of calories or variety of nutrients. Several nutrients in a good prenatal multiple vitamin have been found to benefit pregnant women who suffer from "morning sickness," including vitamin C, vitamin B6, and vitamin K.* The Centers for Disease Control and Prevention recommend folic acid supplementation for all women of childbearing age because the biggest need is during the first trimester, when a woman may not even be aware she is pregnant. A woman who consumes a healthful diet with adequate folate may reduce her risk of having a child with a birth defect of the brain or spinal cord. Folate intake should not exceed 250 percent of the government's recommended daily value (1,000 mcg). The need for other nutrients, such as iron, increases dramatically during pregnancy and is not always compensated for by diet alone.* Multiple vitamin supplementation – during the year before becoming pregnant, during pregnancy, and while breastfeeding – can help produce a healthy baby and benefit the mother through labor, delivery, breastfeeding, and postpartum.* Basic Prenatal by Thorne Research is a comprehensive supplement formulated with the special needs of pregnancy in mind. Manufactured with none of the additives and coatings usually found in mainstream prenatal tablets, Basic Prenatal includes only the most bioavailable nutrients. High-potency multiple vitamins may sometimes be difficult for a woman to "stomach," particularly during the first trimester of pregnancy. Therefore, Thorne does not include large amounts of the nutrients commonly known to cause stomach upset. Instead, these nutrients are included in their most active or absorbable forms for superior utilization.* Among these are the active forms of several of the B vitamins – pyridoxal 5'-phosphate (vitamin B6), riboflavin 5'-phosphate (vitamin B2), folinic acid and L-5-MTHF (active forms of folate), and adenosylcobalamin and methylcobalamin (vitamin B12). Calcium in large doses may also cause stomach upset. Therefore, a moderate dose in the highly absorbable citrate-malate form is used. Additional calcium and magnesium can be supplemented, especially in the final trimester. Basic Prenatal by Thorne Research may also be taken by nursing mothers.   Statements and Warnings ALLERGY WARNINGS Basic Prenatal by Thorne Research is contraindicated in an individual with a history of hypersensitivity to any of its ingredients. Iodine may occasionally cause an allergic reaction in some individuals. PURITY Basic Prenatal by Thorne Research does not contain wheat, gluten, corn, yeast, soy, egg, dairy products, or artificial colors, artificial sweeteners, or artificial flavors. This product also does not contain lactose, palmitic acid, magnesium stearate, or stearic acid. PREGNANCY If pregnant, consult your health-care practitioner before using Basic Prenatal by Thorne Research. INTERACTIONS As vitamin K interferes with the effect of anticoagulant drugs (like Coumadin), the concurrent use of these agents should be avoided. Folinic acid and 5-methyltetrahydrofolate supplementation is not recommended concurrent with methotrexate cancer therapy, as they can interfere with methotrexate's anti-neoplastic activity; however, these folate sources have not been shown to interfere with the anti-inflammatory activity of methotrexate. An individual taking methotrexate for psoriasis or rheumatoid arthritis can safely take a supplement containing folate. ADDITIONAL WARNINGS Accidental overdose of iron-containing products is a leading cause of fatal poisoning in children under six. Keep this product out of reach of children. In case of accidental overdose, call a doctor or poison control center immediately. Vitamin C can cause diarrhea in some individuals in large doses, which can vary from person to person and resolves when the amount is reduced.    Some customers have noted that this formula has a strong odor. This is particularly noticeable to patients who have been taking it long-term. The change in odor is due to the fact that we have (over the past year) changed from selenium picolinate to selenomethionine. While we believe selenomethionine is a superior form of selenium, it does have a bit of a sulfur smell, which is normal and does not reflect a problem with the product.   These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease. Buy FRESH authorized products. We are an authorized distributor of Thorne Research and other fine brands. Questions? Ask the Naturopathic Doctor/Dietician Nutritionist!